Metabolic and vascular risk factors among APOE risk gene subtypes and
relationship to conversion to MCI and dementia
 
   Lead Investigator:    Jagan Pillai
   Institution      :    Cleveland Clinic
   E-Mail           :    pillaij@ccf.org
   Proposal ID      :    1118



   Proposal Description:
   Aim: Among the APOE risk gene subtypes we will determine the differences in the frequency of metabolic and vascular risk factors and related medications among APOE genotypes who convert to MCI or dementia and those who do not. This project will assess if among the APOE gene subtypes if the existence of metabolic or vascular risk factors increase risk of conversion to MCI or dementia from normal cognition longitudinally.